Mutually exclusive inhibition of herpesvirus DNA polymerase by aphidicolin, phosphonoformate, and acyclic nucleoside triphosphates.

Dual inhibitor studies were performed to examine the interaction of aphidicolin, phosphonoformate, 9-(2-hydroxyethoxymethyl)guanine triphosphate, and 9-(1,3-dihydroxy-2-propoxymethyl)guanine triphosphate with herpes simplex virus DNA polymerase. Kinetic data indicated that inhibition by one agent pr...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Frank, K B, Cheng, Y C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180071/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2988429/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.4.445
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