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The Caenorhabditis elegans Replication Licensing Factor CDT-1 Is Targeted for Degradation by the CUL-4/DDB-1 Complex

The replication of genomic DNA is strictly regulated to occur only once per cell cycle. This regulation centers on the temporal restriction of replication licensing factor activity. Two distinct ubiquitin ligase (E3) complexes, CUL4/DDB1 and SCF(Skp2), have been reported to target the replication li...

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Detalhes bibliográficos
Main Authors: Kim, Youngjo, Kipreos, Edward T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800708/
https://ncbi.nlm.nih.gov/pubmed/17145765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00736-06
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