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The Caenorhabditis elegans Replication Licensing Factor CDT-1 Is Targeted for Degradation by the CUL-4/DDB-1 Complex

The replication of genomic DNA is strictly regulated to occur only once per cell cycle. This regulation centers on the temporal restriction of replication licensing factor activity. Two distinct ubiquitin ligase (E3) complexes, CUL4/DDB1 and SCF(Skp2), have been reported to target the replication li...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, Youngjo, Kipreos, Edward T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800708/
https://ncbi.nlm.nih.gov/pubmed/17145765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00736-06
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