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The Caenorhabditis elegans Replication Licensing Factor CDT-1 Is Targeted for Degradation by the CUL-4/DDB-1 Complex

The replication of genomic DNA is strictly regulated to occur only once per cell cycle. This regulation centers on the temporal restriction of replication licensing factor activity. Two distinct ubiquitin ligase (E3) complexes, CUL4/DDB1 and SCF(Skp2), have been reported to target the replication li...

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Bibliografski detalji
Glavni autori: Kim, Youngjo, Kipreos, Edward T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800708/
https://ncbi.nlm.nih.gov/pubmed/17145765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00736-06
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