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The dynamics of replication licensing in live Caenorhabditis elegans embryos

Accurate DNA replication requires proper regulation of replication licensing, which entails loading MCM-2–7 onto replication origins. In this paper, we provide the first comprehensive view of replication licensing in vivo, using video microscopy of Caenorhabditis elegans embryos. As expected, MCM-2–...

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Bibliografische gegevens
Hoofdauteurs: Sonneville, Remi, Querenet, Matthieu, Craig, Ashley, Gartner, Anton, Blow, J. Julian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265957/
https://ncbi.nlm.nih.gov/pubmed/22249291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201110080
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