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Chk2 Mediates Stabilization of the FoxM1 Transcription Factor To Stimulate Expression of DNA Repair Genes

The forkhead box M1 (FoxM1) transcription factor regulates expression of cell cycle genes essential for DNA replication and mitosis during organ repair and cancer progression. Here, we demonstrate that FoxM1-deficient (−/−) mouse embryonic fibroblasts and osteosarcoma U2OS cells depleted in FoxM1 le...

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Detalhes bibliográficos
Main Authors: Tan, Yongjun, Raychaudhuri, Pradip, Costa, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800696/
https://ncbi.nlm.nih.gov/pubmed/17101782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01068-06
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