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A Two-Step, PU.1-Dependent Mechanism for Developmentally Regulated Chromatin Remodeling and Transcription of the c-fms Gene

Hematopoietic stem cells and multipotent progenitors exhibit low-level transcription and partial chromatin reorganization of myeloid cell-specific genes including the c-fms (csf1R) locus. Expression of the c-fms gene is dependent on the Ets family transcription factor PU.1 and is upregulated during...

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Autors principals: Krysinska, Hanna, Hoogenkamp, Maarten, Ingram, Richard, Wilson, Nicola, Tagoh, Hiromi, Laslo, Peter, Singh, Harinder, Bonifer, Constanze
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800675/
https://ncbi.nlm.nih.gov/pubmed/17116688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01915-06
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