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Enhanced efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine in combination with alpha-interferon against herpes simplex virus type 2 in mice.
The acyclic nucleoside DHPG [9-(1,3-dihydroxy-2-propoxymethyl)guanine] and recombinant human alpha-interferon of clones A/D potentiate each other's antiviral activity against a systemic infection with herpes simplex virus type 2. The effective dose at which 50% of the mice survived was lowered...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
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1984
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC180056/ https://ncbi.nlm.nih.gov/pubmed/6335382 |
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