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Kinetics of the interaction of monophosphates of the antiviral nucleosides 2'-fluoro-1-beta-D-arabinofuranosylpyrimidine and (E)-5-(2-bromovinyl)-2'-deoxyuridine with thymidylate kinases from Vero cells and herpes simplex virus types 1 and 2.

The affinities of the monophosphates of 2'-fluoro-5-iodo-1-beta-D-arabinofuranosyluracil and its 5-methyl analog for cellular thymidylate kinase were two or more orders of magnitude greater than for the thymidine-thymidylate kinases from herpes simplex virus types 1 and 2. In contrast, the monophosp...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:Antimicrob Agents Chemother
Үндсэн зохиолчид: Chen, M S, Amico, L A, Speelman, D J
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: American Society for Microbiology (ASM) 1984
Нөхцлүүд:
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6083755/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.5.778
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