Ferredoxin-linked reduction of metronidazole in Clostridium pasteurianum.

Clostridium pasteurianum cell-free extracts enzymatically reduced metronidazole when coupled by hydrogenase via reduced ferredoxin. A 5 mM concentration of methyl viologen, flavin adenine dinucleotide, or flavin mononucleotide could completely replace ferredoxin (0.05 mM) in the in vitro reduction a...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Lockerby, D L, Rabin, H R, Bryan, L E, Laishley, E J
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1984
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179990/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6517554/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.5.665
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