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Mechanism of pyrimethamine resistance in recent isolates of Plasmodium falciparum.

Clones of Plasmodium falciparum prepared from recent isolates of infected blood were studied to determine the molecular mechanism of naturally occurring pyrimethamine resistance. Total DNA, as well as thymidylate synthetase and dihydrofolate reductase activities, were characterized from these lines....

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Principais autores: McCutchan, T F, Welsh, J A, Dame, J B, Quakyi, I A, Graves, P M, Drake, J C, Allegra, C J
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1984
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179988/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6393866/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.5.656
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