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Pharmacokinetics and bacteriological efficacies of apalcillin and cefpiramide in experimental pneumococcal meningitis.

Rabbits with experimentally induced pneumococcal meningitis were given single 25-mg/kg doses of apalcillin or cefpiramide. Mean percentages of the drug concentration in cerebrospinal fluid versus that in blood serum were 7.6% with apalcillin and 3.9% with cefpiramide. Bactericidal activity in cerebr...

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Bibliografische gegevens
Hoofdauteurs: Sato, K, Shelton, S, Nelson, J D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1984
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC179967/
https://ncbi.nlm.nih.gov/pubmed/6517548
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