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Pharmacokinetics and bacteriological efficacies of apalcillin and cefpiramide in experimental pneumococcal meningitis.

Rabbits with experimentally induced pneumococcal meningitis were given single 25-mg/kg doses of apalcillin or cefpiramide. Mean percentages of the drug concentration in cerebrospinal fluid versus that in blood serum were 7.6% with apalcillin and 3.9% with cefpiramide. Bactericidal activity in cerebr...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Sato, K, Shelton, S, Nelson, J D
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1984
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179967/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6517548/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.4.578
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