Comparative pharmacokinetics of Sch 28191 and amphotericin B in mice, rats, dogs, and cynomolgus monkeys.

The pharmacokinetics of Sch 28191, the N-D-ornithyl methyl ester of amphotericin B, and amphotericin B were studied in mice, rats, dogs, and cynomolgus monkeys after an intravenous dose of 0.6 mg/kg was administered. The decline in the concentrations of Sch 28191 and amphotericin B in serum appeared...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Kim, H, Loebenberg, D, Marco, A, Symchowicz, S, Lin, C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1984
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179942/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6517539/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.4.446
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