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Immediate early gene-X1 interferes with 26 S proteasome activity by attenuating expression of the 19 S proteasomal components S5a/Rpn10 and S1/Rpn2

The stress response gene IEX-1 (immediate early gene-X-1) is involved in the regulation of cell growth and cellular viability. To some extent, these effects include an interference with the proteasomal turnover of certain regulatory proteins. Here, we show that IEX-1 directly attenuates the activity...

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Detalhes bibliográficos
Main Authors: Arlt, Alexander, Minkenberg, Jörg, Kruse, Marie-Luise, Grohmann, Frauke, Fölsch, Ulrich R., Schäfer, Heiner
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798431/
https://ncbi.nlm.nih.gov/pubmed/17107344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061072
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