Methotrexate modulates the kinetics of adenosine in humans in vivo

BACKGROUND: Animal studies suggest that the anti‐inflammatory effect of methotrexate (MTX) is mediated by increased adenosine concentrations. OBJECTIVE: To assess the effect of MTX on the vasodilator effects of adenosine and the nucleoside uptake inhibitor, dipyridamole, in humans in vivo as a marke...

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Detalhes bibliográficos
Main Authors: Riksen, N P, Barrera, P, van den Broek, P H H, van Riel, P L C M, Smits, P, Rongen, G A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798086/
https://ncbi.nlm.nih.gov/pubmed/16308339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.048637
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