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Anti‐TNF antibody treatment improves glucocorticoid induced insulin‐like growth factor 1 (IGF1) resistance without influencing myoglobin and IGF1 binding proteins 1 and 3

BACKGROUND: Insulin‐like growth factor 1 (IGF1) is an important determinant of muscle mass because it promotes growth and suppresses protein degradation. IGF1 is decreased in rheumatoid arthritis and juvenile idiopathic arthritis because its synthesis is inhibited by inflammation. In parallel, gluco...

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Detalhes bibliográficos
Main Authors: Sarzi‐Puttini, P, Atzeni, F, Schölmerich, J, Cutolo, M, Straub, R H
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798065/
https://ncbi.nlm.nih.gov/pubmed/16079165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.040816
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