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New Generation of Cell Culture Assay for Smallpox Vaccine Potency
The potency of smallpox vaccines produced in the 1970s was tested by titration onto chorioallantoic membranes of fertilized hen eggs (CAM assay). The potency specification commonly approved for these vaccines was a titer above 10(8) pock-forming units per milliliter. We developed and validated a cel...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC179801/ https://ncbi.nlm.nih.gov/pubmed/12904376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.41.8.3687-3689.2003 |
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