Mouse Potency Assay for Western Equine Encephalomyelitis Vaccines

A potency assay for Western equine encephalomyelitis vaccine was developed which utilized mice as the test animal instead of guinea pigs or hamsters. By immunizing several groups of mice with dilutions of the vaccine and challenging them intracerebrally with virulent virus, it was possible to determ...

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Bibliografiske detaljer
Udgivet i:Appl Microbiol
Main Authors: Robinson, David M., Berman, Sanford, Lowenthal, Joseph P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1972
Fag:
Clinical Microbiology, Virology, and Immunology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC380285/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5059614/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/am.23.1.104-107.1972
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