Assignment of muscarinic receptor subtypes mediating G-protein modulation of Ca(2+) channels by using knockout mice

There are five known subtypes of muscarinic receptors (M(1)–M(5)). We have used knockout mice lacking the M(1), M(2), or M(4) receptors to determine which subtypes mediate modulation of voltage-gated Ca(2+) channels in mouse sympathetic neurons. Muscarinic agonists modulate N- and L-type Ca(2+) chan...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Shapiro, Mark S., Loose, Michael D., Hamilton, Susan E., Nathanson, Neil M., Gomeza, Jesus, Wess, Jürgen, Hille, Bertil
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17980/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10485923/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.19.10899
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