Production and Characterization of High-Affinity Human Monoclonal Antibodies to Human Immunodeficiency Virus Type 1 Envelope Glycoproteins in a Mouse Model Expressing Human Immunoglobulins

Human (Hu) monoclonal antibodies (MAbs) against the human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins (Env) are useful tools in the structural and functional analysis of Env, are under development both as potential prophylaxis and as therapy for established HIV-1 infection, and have...

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Detalhes bibliográficos
Main Authors: Sheppard, Neil C., Davies, Sarah L., Jeffs, Simon A., Vieira, Sueli M., Sattentau, Quentin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Cellular Immunology, Antibodies, and Mediators of Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797789/
https://ncbi.nlm.nih.gov/pubmed/17167037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00274-06
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