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Aspirin Antagonism in Isoniazid Treatment of Tuberculosis in Mice

Salicylate has previously been shown to reduce the susceptibility of Mycobacterium tuberculosis to several drugs in vitro. In this study, aspirin, a salicylate anti-inflammatory, antagonized isoniazid treatment of murine pulmonary tuberculosis, whereas the nonsalicylate ibuprofen did not. These resu...

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Bibliografiska uppgifter
Huvudupphovsmän: Byrne, Sean T., Denkin, Steven M., Zhang, Ying
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797778/
https://ncbi.nlm.nih.gov/pubmed/17145791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01145-06
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