Antagonism between isoniazid and the combination pyrazinamide-rifampin against tuberculosis infection in mice.

Mice that had been inoculated intravenously with 6.30 log10 Mycobacterium tuberculosis H37Rv 14 days earlier were administered one of three combinations of drugs, i.e., isoniazid (INH)-rifampin (RMP)-pyrazinamide (PZA), INH-RMP, and RMP-PZA, during an initial 2-month period to mimic the initial phas...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Grosset, J, Truffot-Pernot, C, Lacroix, C, Ji, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190555/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1622164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.3.548
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