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Lysostaphin-Resistant Variants of Staphylococcus aureus Demonstrate Reduced Fitness In Vitro and In Vivo

Lysostaphin is under development as a therapy for serious staphylococcal infections. During preclinical development, lysostaphin-resistant Staphylococcus aureus variants have occasionally been reported in vitro and in vivo. The acquisition of resistance to this drug, however, leads to a significant...

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Detaylı Bibliyografya
Asıl Yazarlar: Kusuma, Caroline, Jadanova, Anna, Chanturiya, Tanya, Kokai-Kun, John F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797764/
https://ncbi.nlm.nih.gov/pubmed/17101683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00786-06
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