Efficacy of Bacteriophage Therapy against Gut-Derived Sepsis Caused by Pseudomonas aeruginosa in Mice

We evaluated the efficacy of bacteriophage (phage) therapy by using a murine model of gut-derived sepsis caused by Pseudomonas aeruginosa that closely resembles the clinical pathophysiology of septicemia in humans. Oral administration of a newly isolated lytic phage strain (KPP10) significantly prot...

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Detalhes bibliográficos
Main Authors: Watanabe, Ryohei, Matsumoto, Tetsuya, Sano, Go, Ishii, Yoshikazu, Tateda, Kazuhiro, Sumiyama, Yoshinobu, Uchiyama, Jumpei, Sakurai, Shingo, Matsuzaki, Shigenobu, Imai, Shosuke, Yamaguchi, Keizo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797723/
https://ncbi.nlm.nih.gov/pubmed/17116686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00635-06
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