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Association of Fluconazole Area under the Concentration-Time Curve/MIC and Dose/MIC Ratios with Mortality in Nonneutropenic Patients with Candidemia

The present study tested in vitro susceptibility of Candida bloodstream isolates to fluconazole to determine if the ratio of the fluconazole area under the concentration-time curve (AUC) or weight-normalized daily dose (dose(wn)) to MIC correlated with mortality. Fluconazole susceptibility and outco...

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Detalhes bibliográficos
Main Authors: Pai, Manjunath P., Turpin, Robin S., Garey, Kevin W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797664/
https://ncbi.nlm.nih.gov/pubmed/17101684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00474-06
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