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Association of Fluconazole Area under the Concentration-Time Curve/MIC and Dose/MIC Ratios with Mortality in Nonneutropenic Patients with Candidemia

The present study tested in vitro susceptibility of Candida bloodstream isolates to fluconazole to determine if the ratio of the fluconazole area under the concentration-time curve (AUC) or weight-normalized daily dose (dose(wn)) to MIC correlated with mortality. Fluconazole susceptibility and outco...

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Bibliographic Details
Main Authors: Pai, Manjunath P., Turpin, Robin S., Garey, Kevin W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797664/
https://ncbi.nlm.nih.gov/pubmed/17101684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00474-06
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