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Association of Fluconazole Area under the Concentration-Time Curve/MIC and Dose/MIC Ratios with Mortality in Nonneutropenic Patients with Candidemia

The present study tested in vitro susceptibility of Candida bloodstream isolates to fluconazole to determine if the ratio of the fluconazole area under the concentration-time curve (AUC) or weight-normalized daily dose (dose(wn)) to MIC correlated with mortality. Fluconazole susceptibility and outco...

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Autori principali: Pai, Manjunath P., Turpin, Robin S., Garey, Kevin W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797664/
https://ncbi.nlm.nih.gov/pubmed/17101684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00474-06
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