Amoxicillin Is Effective against Penicillin-Resistant Streptococcus pneumoniae Strains in a Mouse Pneumonia Model Simulating Human Pharmacokinetics

High-dose oral amoxicillin (3 g/day) is the recommended empirical outpatient treatment of community-acquired pneumonia (CAP) in many European guidelines. To investigate the clinical efficacy of this treatment in CAP caused by Streptococcus pneumoniae strains with MICs of amoxicillin ≥2 μg/ml, we use...

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Detalhes bibliográficos
Main Authors: Abgueguen, Pierre, Azoulay-Dupuis, Esther, Noel, Violaine, Moine, Pierre, Rieux, Veronique, Fantin, Bruno, Bedos, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797644/
https://ncbi.nlm.nih.gov/pubmed/17060515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00004-06
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