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The Role of Myelin in Theiler's Virus Persistence in the Central Nervous System

Theiler's virus, a picornavirus, persists for life in the central nervous system of mouse and causes a demyelinating disease that is a model for multiple sclerosis. The virus infects neurons first but persists in white matter glial cells, mainly oligodendrocytes and macrophages. The mechanism,...

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Bibliografiska uppgifter
Huvudupphovsmän: Roussarie, Jean-Pierre, Ruffié, Claude, Brahic, Michel
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797621/
https://ncbi.nlm.nih.gov/pubmed/17305428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030023
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