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The Role of Myelin in Theiler's Virus Persistence in the Central Nervous System
Theiler's virus, a picornavirus, persists for life in the central nervous system of mouse and causes a demyelinating disease that is a model for multiple sclerosis. The virus infects neurons first but persists in white matter glial cells, mainly oligodendrocytes and macrophages. The mechanism,...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1797621/ https://ncbi.nlm.nih.gov/pubmed/17305428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030023 |
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