Impaired neutrophil activity and increased susceptibility to bacterial infection in mice lacking glucose-6-phosphatase–β

Neutropenia and neutrophil dysfunction are common in many diseases, although their etiology is often unclear. Previous views held that there was a single ER enzyme, glucose-6-phosphatase–α (G6Pase-α), whose activity — limited to the liver, kidney, and intestine — was solely responsible for the final...

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Bibliographische Detailangaben
Hauptverfasser: Cheung, Yuk Yin, Kim, So Youn, Yiu, Wai Han, Pan, Chi-Jiunn, Jun, Hyun-Sik, Ruef, Robert A., Lee, Eric J., Westphal, Heiner, Mansfield, Brian C., Chou, Janice Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2007
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797608/
https://ncbi.nlm.nih.gov/pubmed/17318259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30443
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