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The Transdominant Endogenous Retrovirus enJS56A1 Associates with and Blocks Intracellular Trafficking of Jaagsiekte Sheep Retrovirus Gag

The sheep genome harbors approximately 20 endogenous retroviruses (enJSRVs) highly related to the exogenous Jaagsiekte sheep retrovirus (JSRV). One of the enJSRV loci, enJS56A1, acts as a unique restriction factor by blocking JSRV in a transdominant fashion at a late stage of the retroviral cycle. T...

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Autores principales: Murcia, Pablo R., Arnaud, Frederick, Palmarini, Massimo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797599/
https://ncbi.nlm.nih.gov/pubmed/17135320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01859-06
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