The Transdominant Endogenous Retrovirus enJS56A1 Associates with and Blocks Intracellular Trafficking of Jaagsiekte Sheep Retrovirus Gag

The sheep genome harbors approximately 20 endogenous retroviruses (enJSRVs) highly related to the exogenous Jaagsiekte sheep retrovirus (JSRV). One of the enJSRV loci, enJS56A1, acts as a unique restriction factor by blocking JSRV in a transdominant fashion at a late stage of the retroviral cycle. T...

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Bibliographic Details
Main Authors: Murcia, Pablo R., Arnaud, Frederick, Palmarini, Massimo
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Genetic Diversity and Evolution
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797599/
https://ncbi.nlm.nih.gov/pubmed/17135320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01859-06
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