Adeno-Associated Virus Site-Specific Integration Is Regulated by TRP-185

Adeno-associated virus (AAV) integrates site specifically into the AAVS1 locus on human chromosome 19. Although recruitment of the AAV nonstructural protein Rep78/68 to the Rep binding site (RBS) on AAVS1 is thought to be an essential step, the mechanism of the site-specific integration, particularl...

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Autors principals: Yamamoto, Noriaki, Suzuki, Masato, Kawano, Masa-aki, Inoue, Takamasa, Takahashi, Ryou-u, Tsukamoto, Hiroko, Enomoto, Teruya, Yamaguchi, Yuki, Wada, Tadashi, Handa, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Genome Replication and Regulation of Viral Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797547/
https://ncbi.nlm.nih.gov/pubmed/17151120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02014-06
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