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The ERK Mitogen-Activated Protein Kinase Pathway Contributes to Ebola Virus Glycoprotein-Induced Cytotoxicity

Ebola virus is a highly lethal pathogen that causes hemorrhagic fever in humans and nonhuman primates. Among the seven known viral gene products, the envelope glycoprotein (GP) alone induces cell rounding and detachment that ultimately leads to cell death. Cellular cytoxicity is not seen with compar...

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Bibliografiska uppgifter
Huvudupphovsmän: Zampieri, Carisa A., Fortin, Jean-Francois, Nolan, Garry P., Nabel, Gary J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797502/
https://ncbi.nlm.nih.gov/pubmed/17108034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01586-06
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