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Variable Deficiencies in the Interferon Response Enhance Susceptibility to Vesicular Stomatitis Virus Oncolytic Actions in Glioblastoma Cells but Not in Normal Human Glial Cells

With little improvement in the poor prognosis for humans with high-grade glioma brain tumors, alternative therapeutic strategies are needed. As such, selective replication-competent oncolytic viruses may be useful as a potential treatment modality. Here we test the hypothesis that defects in the int...

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Detalhes bibliográficos
Main Authors: Wollmann, Guido, Robek, Michael D., van den Pol, Anthony N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797501/
https://ncbi.nlm.nih.gov/pubmed/17108037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01861-06
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