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Variable Deficiencies in the Interferon Response Enhance Susceptibility to Vesicular Stomatitis Virus Oncolytic Actions in Glioblastoma Cells but Not in Normal Human Glial Cells

With little improvement in the poor prognosis for humans with high-grade glioma brain tumors, alternative therapeutic strategies are needed. As such, selective replication-competent oncolytic viruses may be useful as a potential treatment modality. Here we test the hypothesis that defects in the int...

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Autors principals: Wollmann, Guido, Robek, Michael D., van den Pol, Anthony N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797501/
https://ncbi.nlm.nih.gov/pubmed/17108037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01861-06
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