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The Level of CD81 Cell Surface Expression Is a Key Determinant for Productive Entry of Hepatitis C Virus into Host Cells

Recently a cell culture model supporting the complete life cycle of the hepatitis C virus (HCV) was developed. Searching for host cell determinants involved in the HCV replication cycle, we evaluated the efficiency of virus propagation in different Huh-7-derived cell clones. We found that Huh-7.5 ce...

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Autori principali: Koutsoudakis, George, Herrmann, Eva, Kallis, Stephanie, Bartenschlager, Ralf, Pietschmann, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797465/
https://ncbi.nlm.nih.gov/pubmed/17079281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01534-06
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