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Identification of a Secreted Cholesterol-Dependent Cytolysin (Mitilysin) from Streptococcus mitis

We have detected a cholesterol-dependent cytolysin, which we have named mitilysin, in a small number of Streptococcus mitis isolates. We have sequenced the mitilysin gene from seven isolates of S. mitis. Comparisons with the pneumococcal pneumolysin gene show 15 amino acid substitutions. S. mitis ap...

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Main Authors: Jefferies, Johanna, Nieminen, Leena, Kirkham, Lea-Ann, Johnston, Calum, Smith, Andrew, Mitchell, Tim J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797409/
https://ncbi.nlm.nih.gov/pubmed/17071760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01092-06
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