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Identification of a Secreted Cholesterol-Dependent Cytolysin (Mitilysin) from Streptococcus mitis

We have detected a cholesterol-dependent cytolysin, which we have named mitilysin, in a small number of Streptococcus mitis isolates. We have sequenced the mitilysin gene from seven isolates of S. mitis. Comparisons with the pneumococcal pneumolysin gene show 15 amino acid substitutions. S. mitis ap...

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Detalhes bibliográficos
Main Authors: Jefferies, Johanna, Nieminen, Leena, Kirkham, Lea-Ann, Johnston, Calum, Smith, Andrew, Mitchell, Tim J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797409/
https://ncbi.nlm.nih.gov/pubmed/17071760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01092-06
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