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Human T-Cell Leukemia Virus Type 1 Tax Protein Down-Regulates Pre-T-Cell Receptor Alpha Gene Transcription in Human Immature Thymocytes

The human pre-T-cell receptor alpha (TCRα; pTα) gene encodes a polypeptide which associates with the TCRβ chain and CD3 molecules to form the pre-TCR complex. The surface expression of the pre-TCR is pTα dependent, and signaling through this complex triggers an early αβ T-cell developmental checkpoi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wencker, Mélanie, Sausse, Céline, Derse, David, Gazzolo, Louis, Duc Dodon, Madeleine
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2007
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797236/
https://ncbi.nlm.nih.gov/pubmed/17050604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00766-06
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