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Analysis of the replication of HIV-1 forced to use tRNA(Met(i) )supports a link between primer selection, translation and encapsidation

BACKGROUND: Previous studies have suggested that the process of HIV-1 tRNA primer selection and encapsidation of genomic RNA might be coupled with viral translation. In order to further investigate this relationship, proviruses were constructed in which the primer-binding site (PBS) was altered to b...

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Hlavní autoři: Djekic, Uros V, Morrow, Casey D
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797187/
https://ncbi.nlm.nih.gov/pubmed/17274824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-10
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