Selective defect of in vivo glycolysis in early Huntington's disease striatum

Activity of complexes II, III, and IV of the mitochondrial electron transport system (ETS) is reduced in postmortem Huntington's disease (HD) striatum, suggesting that reduced cerebral oxidative phosphorylation may be important in the pathogenesis of neuronal death. We investigated mitochondria...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Powers, William J., Videen, Tom O., Markham, Joanne, McGee-Minnich, Lori, Antenor-Dorsey, JoAnn V., Hershey, Tamara, Perlmutter, Joel S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2007
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797149/
https://ncbi.nlm.nih.gov/pubmed/17299049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609833104
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