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Protein Phosphatase 6 Down-Regulates TAK1 Kinase Activation in the IL-1 Signaling Pathway

TAK1 is a serine/threonine kinase that is a mitogen-activated protein kinase kinase kinase (MAPKKK), and an essential intracellular signaling component in inflammatory signaling pathways. Upon stimulation of cells with inflammatory cytokines, TAK1 binds proteins that stimulate autophosphorylation wi...

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Detalhes bibliográficos
Main Authors: Kajino, Taisuke, Ren, Hong, Iemura, Shun-ichiro, Natsume, Tohru, Stefansson, Bjarki, Brautigan, David L., Matsumoto, Kunihiro, Ninomiya-Tsuji, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797071/
https://ncbi.nlm.nih.gov/pubmed/17079228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M608155200
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