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Tak1 is a Master Regulator of Epidermal Homeostasis Involving Skin Inflammation and Apoptosis
TAK1 functions downstream of inflammatory cytokines to activate c-Jun N-terminal kinase (JNK) as well as NF-κB in several cell types. However, the functional role of TAK1 in an in vivo setting has not been determined. Here we demonstrate that TAK1 is the major regulator of skin inflammation as well...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1797070/ https://ncbi.nlm.nih.gov/pubmed/16675448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M603384200 |
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