Factor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer

BACKGROUND: Alterations of chromosome 8 and hypomethylation of LINE-1 retrotransposons are common alterations in advanced prostate carcinoma. In a former study including many metastatic cases, they strongly correlated with each other. To elucidate a possible interaction between the two alterations,...

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Détails bibliographiques
Auteurs principaux: Schulz, Wolfgang A, Alexa, Adrian, Jung, Volker, Hader, Christiane, Hoffmann, Michèle J, Yamanaka, Masanori, Fritzsche, Sandy, Wlazlinski, Agnes, Müller, Mirko, Lengauer, Thomas, Engers, Rainer, Florl, Andrea R, Wullich, Bernd, Rahnenführer, Jörg
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2007
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797054/
https://ncbi.nlm.nih.gov/pubmed/17280610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-6-14
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