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Reduction of gene repair by selenomethionine with the use of single-stranded oligonucleotides

BACKGROUND: The repair of single base mutations in mammalian genes can be directed by single-stranded oligonucleotides in a process known as targeted gene repair. The mechanism of this reaction is currently being elucidated but likely involves a pairing step in which the oligonucleotide align in hom...

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Autores principales: Schwartz, Timothy R, Kmiec, Eric B
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797052/
https://ncbi.nlm.nih.gov/pubmed/17257432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-7
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