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Molecular Dynamics Simulation Suggests Possible Interaction Patterns at Early Steps of β(2)-Microglobulin Aggregation
Early events in aggregation of proteins are not easily accessible by experiments. In this work, we perform a 5-ns molecular dynamics simulation of an ensemble of 27 copies of β(2)-microglobulin in explicit solvent. During the simulation, the formation of intermolecular contacts is observed. The simu...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Biophysical Society
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1796822/ https://ncbi.nlm.nih.gov/pubmed/17158575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.098483 |
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