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The Influence of Interdomain Interactions on the Intradomain Motions in Yeast Phosphoglycerate Kinase: A Molecular Dynamics Study

A 3-ns molecular dynamics simulation in explicit solvent was performed to examine the inter- and intradomain motions of the two-domain enzyme yeast phosphoglycerate kinase without the presence of substrates. To elucidate contributions from individual domains, simulations were carried out on the comp...

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Main Authors: Balog, Erika, Laberge, Monique, Fidy, Judit
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796818/
https://ncbi.nlm.nih.gov/pubmed/17158564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.093195
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