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Interferon gene transfer by a hepatitis B virus vector efficiently suppresses wild-type virus infection

Hepatitis B viruses specifically target the liver, where they efficiently infect quiescent hepatocytes. Here we show that human and avian hepatitis B viruses can be converted into vectors for liver-directed gene transfer. These vectors allow hepatocyte-specific expression of a green fluorescent prot...

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Bibliografiske detaljer
Main Authors: Protzer, Ulrike, Nassal, Michael, Chiang, Pei-Wen, Kirschfink, Michael, Schaller, Heinz
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC17966/
https://ncbi.nlm.nih.gov/pubmed/10485909
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