Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4-hydroxynonenal

4-Hydroxynonenal (HNE), a lipid peroxidation end product, is produced abundantly in osteoarthritic (OA) articular tissues, but its role in bone metabolism is ill-defined. In this study, we tested the hypothesis that alterations in OA osteoblast metabolism are attributed, in part, to increased levels...

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Detalhes bibliográficos
Main Authors: Shi, Qin, Vaillancourt, France, Côté, Véronique, Fahmi, Hassan, Lavigne, Patrick, Afif, Hassan, Di Battista, John A, Fernandes, Julio C, Benderdour, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794501/
https://ncbi.nlm.nih.gov/pubmed/17042956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2066
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