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Least-squares methods for identifying biochemical regulatory networks from noisy measurements

BACKGROUND: We consider the problem of identifying the dynamic interactions in biochemical networks from noisy experimental data. Typically, approaches for solving this problem make use of an estimation algorithm such as the well-known linear Least-Squares (LS) estimation technique. We demonstrate t...

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Detalhes bibliográficos
Main Authors: Kim, Jongrae, Bates, Declan G, Postlethwaite, Ian, Heslop-Harrison, Pat, Cho, Kwang-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1793997/
https://ncbi.nlm.nih.gov/pubmed/17212835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-8
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