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RNAs that bind and change the permeability of phospholipid membranes

The RNA world hypothesis presumes that RNA will be competent for varied essential cellular functions. One such indispensable cell function is regulation of membrane permeability. Though this was not a known RNA activity, selection–amplification yielded RNAs that bound phosphatidylcholine:cholesterol...

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Autors principals: Khvorova, Anastasia, Kwak, Yong-Geun, Tamkun, Michael, Majerfeld, Irene, Yarus, Michael
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC17937/
https://ncbi.nlm.nih.gov/pubmed/10485880
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